💪🧬🥇NOW 7 INTERNATIONAL PUBLICATIONS (and more to come) TO ATTEST THE ROBUSTNESS AND EFFICIENCY OF EX VIVO CLINICAL APPROACH – CLINIC’N’CELL

https://pubmed.ncbi.nlm.nih.gov/37111121/

Nutrients 2023 Apr 14;15(8):1903. doi: 10.3390/nu15081903.

Circulating Human Metabolites Resulting from TOTUM-070 Absorption (a Plant-Based, Polyphenol-Rich Ingredient) Improve Lipid Metabolism in Human Hepatocytes: Lessons from an Original Ex Vivo Clinical Trial

Fabien Wauquier 1, Line Boutin-Wittrant 1, Stéphanie Krisa 2, Josep Valls 2 3, Cedric Langhi 4, Yolanda F Otero 4, Pascal Sirvent 4, Sébastien Peltier 5, Maxime Bargetto 5, Murielle Cazaubiel 5, Véronique Sapone 5, Annie Bouchard-Mercier 6, Véronique Roux 7, Nicolas Macian 7, Gisèle Pickering 7, Yohann Wittrant 8 9

clinicncell / clinic’n’cell

# EX VIVO CLINICAL TRIAL
Valbiotis annonce les résultats positifs de l’étude clinique de biodisponibilité et de mode d’action de TOTUM•070 contre l’hypercholestérolémie

https://www.ahajournals.org/doi/abs/10.1161/circ.146.suppl_1.11397?af=R

This clinical innovative approach provides robust human data regarding the health benefits of a product in faster, more affordable and more mechanistic ways (mode of action in humans) than any conventional clinical trial. Using human metabolites (circulating and bioavailable bioactives) this approach is more physiological than any in vitro test. The approach is also intended to be ethical since it allow to get rid of an animal experimentation. #clinicncell #clinic’n’cell

AND ONE MORE PUBLICATION… FOR CLINICNCELL = NOW 6 INTERNATIONAL PEER REVIEWED MANUSCRITS AND ONGOING

https://pubmed.ncbi.nlm.nih.gov/36501057/

Nutrients 2022 Nov 25;14(23):5027. doi: 10.3390/nu14235027

Benefits of Circulating Human Metabolites from Fish Cartilage Hydrolysate on Primary Human Dermal Fibroblasts, an Ex Vivo Clinical Investigation for Skin Health Applications.

Fabien Wauquier 1, Line Boutin-Wittrant 1, Elodie Bouvret 2, Julie Le Faouder 2, Véronique Roux 3, Nicolas Macian 3, Gisèle Pickering 3, Yohann Wittrant 4 5

ClinicnCell

🍾 🏆 🥇🔬CLINIC’N’CELL SAS has just obtained the renewal of its CIR approval for 2023 – 2024 and 2025. A great recognition from the General Direction of Research and Innovation of the French Ministry of Higher Education and Research

This clinical innovation provides robust human data regarding the health benefits of a product in faster, more affordable and more mechanistic ways (mode of action in humans) than any conventional clinical trial. Using human metabolites (circulating and bioavailable bioactives) this approach is more physiological than any in vitro test. The approach is also intended to be ethical since it allow to get rid of an animal experimentation. #clinicncell #clinic’n’cell

ANOTHER PUBLICATION TO ATTEST THE ROBUSTNESS OF OUR EX VIVO CLINICAL APPROACH – CLINICNCELL – (NOW 5 MANUSCRITS AND ONGOING)

https://pubmed.ncbi.nlm.nih.gov/35406124/

Nutrients 2022 Apr 5;14(7):1511. doi: 10.3390/nu14071511.

Circulating Human Serum Metabolites Derived from the Intake of a Saffron Extract (Safr’InsideTM) Protect Neurons from Oxidative Stress: Consideration for Depressive Disorders

Fabien Wauquier 1, Line Boutin-Wittrant 1, Line Pourtau 2, David Gaudout 2, Benjamin Moras 2, Adeline Vignault 2, Camille Monchaux De Oliveira 2, Julien Gabaston 2, Carole Vaysse 3, Karène Bertrand 3, Hélène Abrous 3, Lucile Capuron 4 5, Nathalie Castanon 4 5, David Vauzour 6, Véronique Roux 7, Nicolas Macian 7, Gisèle Pickering 7, Yohann Wittrant 8 9

CLINICNCELL sponsors and participates to the European Calcified Tissue Society PhD Training Course 2022

This prestigious PhD Training Course, aimed at promoting general knowledge of bone research to young investigators, is now in its 15th year and has been hailed as one of the most innovative and successful courses in the bone field.

The course starts with an “introductory session” where key topics relevant to skeletal research are covered, followed by a varied programme that incorporates clinical and basic topics with a mix of speakers with clinical or basic science backgrounds. An example of the topics likely to be included in the programme is provided below. One of the important aspects of the course is the opportunity for students to network and obtain feedback on their project. Student presentations include poster and short presentations of their PhD project as well as networking sessions with invited speakers. The course has been of immense value to previous participants, and the networks that form during these events help to sustain the musculoskeletal field in Europe into the future.

CLINICNCELL proud winner 2022 NutraIngredients Europe Awards – Start-Up 🏆🥇🔬🧪🧬🍾

We are very pleased to announce that

CLINICNCELL is the proud winner of the 2022 European Contest NutraIngredients Europe Awards

for the category Start-Up of the year 2022.🏆🥇🔬🧪🧬🍾 @NutraEurope and #NIawards22.

We would like to thank the organizing committee and the referees for evaluating and selecting our clinical ex vivo approach 🙏. We also would like to congratulate the other finalists that made the level of the contest so high.

We are very excited to attend the awards ceremony on May 11th in Geneva during Vitafoods 2022 the world’s nutraceutical event. Hope to see you there.

#nutrition #innovations #clinicncell

WHAT THE JUDGES SAID: Ex Vivo, a novel rapid testing technology that can demonstrate health benefits and validate clinical investments, impressed the judges the most. ClinicnCell’s potential impact on consumer health, innovative approach linking human metabolism to cellular biology, long-term vision, and commercial viability strongly resonated with the judging panel, making it the clear winner of the Start-up of the Year category

http://nutraingredients-awards.com/live/en/page/brochure

CLINICNCELL finalist NutraIngredients Europe Awards 2022 🏆🔬🧪🧬

CLINICNCELL is proud to be finalist of the 2022 European Contest NutraIngredients Europe Awards for the category Start-Up. In a sport spirit we wish best luck to the two others selected finalists 👍.

Winner will be celebrated on May 4th. 🏆🍾 #nutrition #innovations

ClinicnCell SAS proposes Ex Vivo Clinical Trials linking human metabolism to cellular biology. ClinicnCell is an academic-developed and protected innovative clinical approach that uses human circulating bioactive metabolites to determine their biological activity on any human cells. Thus, ClinicnCell provides robust human data regarding the health benefit of a nutritional product in more rapid (about 5-10X faster), more affordable (about 10X less expensive) and more mechanistic ways (mode of action in human) than any conventional clinical trials.

Using bioavailable human metabolites, ClinicnCell approach is more physiological than any in vitro assays. It also addresses ethical issues avoiding animal testing for physiological and mechanistic exploration.