The idea of Clinic’n’Cell SAS “Ex Vivo Clinical Trials” was born at the Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement

ClinicnCell offers Ex Vivo Clinical Trials / A methodology protected by INRAE and UCA DIRV#18-000158

ClinicnCell is accredited by the

Ministère de l’Enseignement Supérieur

de la Recherche et de l’Innovation

ClinicnCell awarded by BPI FRANCE

ClinicnCell was proundly launched by BUSI (now part of Clermont Auvergne Innovation)

ClinicnCell awarded at the Clermont Innovation contest

Benefits of Circulating Human Metabolites from Fish Cartilage Hydrolysate on Primary Human Dermal Fibroblasts, an Ex Vivo Clinical Investigation for Skin Health Applications

Fabien Wauquier, Line Boutin-Wittrant, Elodie Bouvret, Julie Le Faouder, Véronique Roux, Nicolas Macian, Gisèle Pickering, Yohann Wittrant

Nutrients. 2022 Nov 25;14(23):5027. doi: 10.3390/nu14235027. / clinicncell

Circulating Human Serum Metabolites Derived from the Intake of a Saffron Extract (Safr’InsideTM) Protect Neurons from Oxidative Stress: Consideration for Depressive Disorders.

Wauquier F, Boutin-Wittrant L, Pourtau L, Gaudout D, Moras B, Vignault A, Monchaux De Oliveira C, Gabaston J, Vaysse C, Bertrand K, Abrous H, Capuron L, Castanon N, Vauzour D, Roux V, Macian N, Pickering G, Wittrant Y.

Nutrients. 2022 Apr 5;14(7):1511. doi: 10.3390/nu14071511. / clinicncell

Metabolic and Anti-Inflammatory Protective Properties of Human Enriched Serum Following Artichoke Leaf Extract Absorption: Results from an Innovative Ex Vivo Clinical Trial.

Wauquier F, Boutin-Wittrant L, Viret A, Guilhaudis L, Oulyadi H, Bourafai-Aziez A, Charpentier G, Rousselot G, Cassin E, Descamps S, Roux V, Macian N, Pickering G, Wittrant Y.

Nutrients. 2021 Jul 30;13(8):2653. doi: 10.3390/nu13082653. PMID: 34444810 / clinicncell

Chondroprotective Properties of Human-Enriched Serum Following Polyphenol Extract Absorption: Results from an Exploratory Clinical Trial.

Wauquier F, Mevel E, Krisa S, Richard T, Valls J, Hornedo-Ortega R, Granel H, Boutin-Wittrant L, Urban N, Berger J, Descamps S, Guicheux J, Vinatier CS, Beck L, Meunier N, Blot A, Wittrant Y.

Nutrients. 2019 Dec 16;11(12):3071. doi: 10.3390/nu11123071. PMID: 31888255 / clinicncell

Non-targeted and targeted analysis of collagen hydrolysates during the course of digestion and absorption.

Kleinnijenhuis AJ, van Holthoon FL, Maathuis AJH, Vanhoecke B, Prawitt J, Wauquier F, Wittrant Y.

Anal Bioanal Chem. 2020 Feb;412(4):973-982.

doi: 10.1007/s00216-019-02323-x. PMID: 31872275 / clinicncell

Human Enriched Serum Following Hydrolysed Collagen Absorption Modulates Bone Cell Activity: from Bedside to Bench and Vice Versa.

Wauquier F, Daneault A, Granel H, Prawitt J, Fabien Soulé V, Berger J, Pereira B, Guicheux J, Rochefort GY, Meunier N, Blot A, Wittrant Y.

Nutrients. 2019 May 31;11(6):1249.

doi: 10.3390/nu11061249. PMID: 31159319 / clinicncell