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Ph.D Cellular and Molecular Biology / Former INRAE researcher / Former post-doctoral fellow at the UTHSCSA (USA) / Inventor / Co-founder
Clinical Research Administration / Co-founder / Former executive assistant at the Centre de Recherche en Nutrition Auvergne (CRNH)
Ph.D Cellular biology / HDR / INRAE senior researcher / University of Texas (USA - NIH grant) / Business School / Inventor
Our expertise for human ex vivo clinical trials are now developped for animal care. Contact us for more details on these new clinical tools for veterinary approach. contact@clinicncell.com
https://pubmed.ncbi.nlm.nih.gov/37111121/
Nutrients 2023 Apr 14;15(8):1903. doi: 10.3390/nu15081903.
Circulating Human Metabolites Resulting from TOTUM-070 Absorption (a Plant-Based, Polyphenol-Rich Ingredient) Improve Lipid Metabolism in Human Hepatocytes: Lessons from an Original Ex Vivo Clinical Trial
Fabien Wauquier 1, Line Boutin-Wittrant 1, Stéphanie Krisa 2, Josep Valls 2 3, Cedric Langhi 4, Yolanda F Otero 4, Pascal Sirvent 4, Sébastien Peltier 5, Maxime Bargetto 5, Murielle Cazaubiel 5, Véronique Sapone 5, Annie Bouchard-Mercier 6, Véronique Roux 7, Nicolas Macian 7, Gisèle Pickering 7, Yohann Wittrant 8 9
clinicncell / clinic’n’cell
Les fondateurs de ClinicnCell sont ravis et honorés de rejoindre le Groupement des Industries de Santé et du Médicament de la Région Auvergne pour partager expériences, expertise et convivialité #GIMRA
https://www.gimra.info/les-actualites/
https://www.gimra.info/bienvenue-a-clinicncell/
https://www.ahajournals.org/doi/abs/10.1161/circ.146.suppl_1.11397?af=R
This clinical innovative approach provides robust human data regarding the health benefits of a product in faster, more affordable and more mechanistic ways (mode of action in humans) than any conventional clinical trial. Using human metabolites (circulating and bioavailable bioactives) this approach is more physiological than any in vitro test. The approach is also intended to be ethical since it allow to get rid of an animal experimentation. #clinicncell #clinic’n’cell
https://pubmed.ncbi.nlm.nih.gov/36501057/
Nutrients 2022 Nov 25;14(23):5027. doi: 10.3390/nu14235027
Benefits of Circulating Human Metabolites from Fish Cartilage Hydrolysate on Primary Human Dermal Fibroblasts, an Ex Vivo Clinical Investigation for Skin Health Applications.
Fabien Wauquier 1, Line Boutin-Wittrant 1, Elodie Bouvret 2, Julie Le Faouder 2, Véronique Roux 3, Nicolas Macian 3, Gisèle Pickering 3, Yohann Wittrant 4 5
ClinicnCell
This clinical innovation provides robust human data regarding the health benefits of a product in faster, more affordable and more mechanistic ways (mode of action in humans) than any conventional clinical trial. Using human metabolites (circulating and bioavailable bioactives) this approach is more physiological than any in vitro test. The approach is also intended to be ethical since it allow to get rid of an animal experimentation. #clinicncell #clinic’n’cell
https://pubmed.ncbi.nlm.nih.gov/35406124/
Nutrients 2022 Apr 5;14(7):1511. doi: 10.3390/nu14071511.
Fabien Wauquier 1, Line Boutin-Wittrant 1, Line Pourtau 2, David Gaudout 2, Benjamin Moras 2, Adeline Vignault 2, Camille Monchaux De Oliveira 2, Julien Gabaston 2, Carole Vaysse 3, Karène Bertrand 3, Hélène Abrous 3, Lucile Capuron 4 5, Nathalie Castanon 4 5, David Vauzour 6, Véronique Roux 7, Nicolas Macian 7, Gisèle Pickering 7, Yohann Wittrant 8 9
This prestigious PhD Training Course, aimed at promoting general knowledge of bone research to young investigators, is now in its 15th year and has been hailed as one of the most innovative and successful courses in the bone field.
The course starts with an “introductory session” where key topics relevant to skeletal research are covered, followed by a varied programme that incorporates clinical and basic topics with a mix of speakers with clinical or basic science backgrounds. An example of the topics likely to be included in the programme is provided below. One of the important aspects of the course is the opportunity for students to network and obtain feedback on their project. Student presentations include poster and short presentations of their PhD project as well as networking sessions with invited speakers. The course has been of immense value to previous participants, and the networks that form during these events help to sustain the musculoskeletal field in Europe into the future.