💪🧬🥇2024 / 9th INTERNATIONAL PEER-REVIEWED PUBLICATIONS – EX VIVO CLINICAL APPROACH – CLINIC’N’CELL
https://pubmed.ncbi.nlm.nih.gov/38543230/
Pharmaceutics. 2024 Feb 28;16(3):336. doi: 10.3390/pharmaceutics16030336.
Reduced Production of Pro-Inflammatory and Pro-Catabolic Factors by Human Serum Metabolites Derived from a Patented Saffron Extract Intake
Line Pourtau 1, Fabien Wauquier 2, Line Boutin-Wittrant 2, David Gaudout 1, Benjamin Moras 1, Adeline Vignault 1, Carole Vaysse 3, Tristan Richard 4 5, Arnaud Courtois 4 5, Stéphanie Krisa 4 5, Véronique Roux 6, Nicolas Macian 6, Gisèle Pickering 6, Yohann Wittrant 2 7 8
💪🧬🥇2024 / 8th INTERNATIONAL PEER-REVIEWED PUBLICATIONS TO ATTEST THE ROBUSTNESS AND EFFICIENCY OF EX VIVO CLINICAL APPROACH – CLINIC’N’CELL
https://pubmed.ncbi.nlm.nih.gov/37735385/
Randomized Controlled Trial
BMC Musculoskelet Disord. 2023 Sep 21;24(1):748. doi:10.1186/s12891-023-06800-4.
Oral supplementation with fish cartilage hydrolysate in an adult population suffering from knee pain and function discomfort: results from an innovative approach combining an exploratory clinical study and an ex vivo clinical investigation
Henrotin Yves 1 2, Julie Herman 3, Melanie Uebelhoer 3, Fabien Wauquier 4, Line Boutin-Wittrant 4, Anne-Françoise Donneau 5, Justine Monseur 5, Variance Mokam Fotso 3, Marie Duquenne 6, Mélanie Wagner 7, Elodie Bouvret 8, Bérénice Costes 3, Yohann Wittrant 9 10
🐶😸🐎🐑🐮Clinic’n’Cell for veterinary clinical investigations
Our expertise for human ex vivo clinical trials are now developped for animal care. Contact us for more details on these new clinical tools for veterinary approach. contact@clinicncell.com
💪🧬🥇NOW 7 INTERNATIONAL PUBLICATIONS (and more to come) TO ATTEST THE ROBUSTNESS AND EFFICIENCY OF EX VIVO CLINICAL APPROACH – CLINIC’N’CELL
https://pubmed.ncbi.nlm.nih.gov/37111121/
Nutrients 2023 Apr 14;15(8):1903. doi: 10.3390/nu15081903.
Circulating Human Metabolites Resulting from TOTUM-070 Absorption (a Plant-Based, Polyphenol-Rich Ingredient) Improve Lipid Metabolism in Human Hepatocytes: Lessons from an Original Ex Vivo Clinical Trial
Fabien Wauquier 1, Line Boutin-Wittrant 1, Stéphanie Krisa 2, Josep Valls 2 3, Cedric Langhi 4, Yolanda F Otero 4, Pascal Sirvent 4, Sébastien Peltier 5, Maxime Bargetto 5, Murielle Cazaubiel 5, Véronique Sapone 5, Annie Bouchard-Mercier 6, Véronique Roux 7, Nicolas Macian 7, Gisèle Pickering 7, Yohann Wittrant 8 9
clinicncell / clinic’n’cell
ClinicnCell rejoint le GIMRA
Les fondateurs de ClinicnCell sont ravis et honorés de rejoindre le Groupement des Industries de Santé et du Médicament de la Région Auvergne pour partager expériences, expertise et convivialité #GIMRA
# EX VIVO CLINICAL TRIAL
https://www.ahajournals.org/doi/abs/10.1161/circ.146.suppl_1.11397?af=R
This clinical innovative approach provides robust human data regarding the health benefits of a product in faster, more affordable and more mechanistic ways (mode of action in humans) than any conventional clinical trial. Using human metabolites (circulating and bioavailable bioactives) this approach is more physiological than any in vitro test. The approach is also intended to be ethical since it allow to get rid of an animal experimentation. #clinicncell #clinic’n’cell
AND ONE MORE PUBLICATION… FOR CLINICNCELL = NOW 6 INTERNATIONAL PEER REVIEWED MANUSCRITS AND ONGOING
https://pubmed.ncbi.nlm.nih.gov/36501057/
Nutrients 2022 Nov 25;14(23):5027. doi: 10.3390/nu14235027
Benefits of Circulating Human Metabolites from Fish Cartilage Hydrolysate on Primary Human Dermal Fibroblasts, an Ex Vivo Clinical Investigation for Skin Health Applications.
Fabien Wauquier 1, Line Boutin-Wittrant 1, Elodie Bouvret 2, Julie Le Faouder 2, Véronique Roux 3, Nicolas Macian 3, Gisèle Pickering 3, Yohann Wittrant 4 5
ClinicnCell
🍾 🏆 🥇🔬CLINIC’N’CELL SAS has just obtained the renewal of its CIR approval for 2023 – 2024 and 2025. A great recognition from the General Direction of Research and Innovation of the French Ministry of Higher Education and Research
This clinical innovation provides robust human data regarding the health benefits of a product in faster, more affordable and more mechanistic ways (mode of action in humans) than any conventional clinical trial. Using human metabolites (circulating and bioavailable bioactives) this approach is more physiological than any in vitro test. The approach is also intended to be ethical since it allow to get rid of an animal experimentation. #clinicncell #clinic’n’cell
ANOTHER PUBLICATION TO ATTEST THE ROBUSTNESS OF OUR EX VIVO CLINICAL APPROACH – CLINICNCELL – (NOW 5 MANUSCRITS AND ONGOING)
https://pubmed.ncbi.nlm.nih.gov/35406124/
Nutrients 2022 Apr 5;14(7):1511. doi: 10.3390/nu14071511.
Circulating Human Serum Metabolites Derived from the Intake of a Saffron Extract (Safr’InsideTM) Protect Neurons from Oxidative Stress: Consideration for Depressive Disorders
Fabien Wauquier 1, Line Boutin-Wittrant 1, Line Pourtau 2, David Gaudout 2, Benjamin Moras 2, Adeline Vignault 2, Camille Monchaux De Oliveira 2, Julien Gabaston 2, Carole Vaysse 3, Karène Bertrand 3, Hélène Abrous 3, Lucile Capuron 4 5, Nathalie Castanon 4 5, David Vauzour 6, Véronique Roux 7, Nicolas Macian 7, Gisèle Pickering 7, Yohann Wittrant 8 9